Assistant Professor

Dr Debabrata Pramanik

Department of Physics


  1. Computational Biophysics
  2. Statistical Physics
  3. Rare Events Sampling



Midnapore College/ Vidyasagar University


Indian Institute of Technology Madras (IITM)


Indian Institute of Science (IISc) Bangalore


  • Aug 2019 – Jun 2022, Postdoctoral Fellow, Indian Institute of Technology Kanpur
  • Mar 2018 – July 2019, Postdoctoral Fellow, University of Maryland College Park, MD, USA
  • May 2017 – Feb 2018, Research Associate, Indian Institute of Science (IISc) Bangalore

Research Interest

  • Elucidating structural and thermodynamic properties of biopolymer – nanomaterial complexes and developing novel nanomaterial composites
  • Developing methods to optimize reaction coordinate
  • High – throughput screening of new chemical entities and developing new drug inhibitors
  • Multicomponent lipid bilayer – drug interaction and spontaneous curvature in membrane bilayer
  • DNA – protein, Ligand – protein, protein – protein interaction and uncovering thermodynamics, kinetics, pathways and mechanistic insights
  • Investigating homogeneous and heterogeneous nucleation. Exploring the effect of small molecules on nucleation of water at the supercool regime

Awards & Fellowships

  • 2014-2015, “UGC BSR Research Fellowship in Science”, UGC, Government of India.
  • 2012-2013, “UGC BSR Research Fellowship in Science”, UGC, Government of India.
  • 2012, Senior Research Fellowship, Indian Institute of Science (IISc) Bangalore.
  • 2010, GATE (Physics), IITs.
  • 2010, JEST (Physics), Research Institute, India.
  • 2008-2009, Meritorious Scholarship, Indian Institute of Technology Madras (IITM), Chennai.
  • 2008, Joint Admission Test for M.Sc. (JAM), IITs.
  • 2008, 1st class 1st, B. Sc. (Physics Hon’s), Vidyasagar University, West Bengal.
  • 2008, Dr. N. C. Rana Memorial Endowment Medal, Vidyasagar University, West Bengal.
  • 2008, Institute Meritorious Scholarship, Midnapore College, West Bengal.
  • 2008, Institute Medal, Midnapore College, West Bengal.


  • Structure of a carbon nanotube-dendrimer composite – V. Vasumathi, D. Pramanik, A. K. Sood, Prabal K. Maiti Soft Matter 9, 1372-1380 (2013)
  • Confinement induced stochastic sensing of charged coronene and perylene aggregates in α-hemolysin nanochannel - R. Shivanna, D. Pramanik, H. Kumar, K. Venkata Rao, Subi J. George, Prabal K. Maiti, K. S. Narayan Soft Matter, 9, 10196-10202 (2013)
  • Graphene and Carbon Nanotube-Based Nanomaterial: Application in Biomedical and Energy Research - H. Kumar, D. Pramanik, S. Mogurampelly, V. Vasumathi, B. Nandy, Prabal K. Maiti; Handbook of Carbon Nano Materials (Graphene Volumes), Vol. 6th, edited by Karl M. Kadish and Francis Dsouza, World Scientifc Press (2014)
  • Dendrimer assisted dispersion of carbon nanotubes: a molecular dynamics study - D. Pramanik, Prabal K. Maiti Soft Matter, 12, 8512-8520 (2016)
  • DNA assisted dispersion of carbon nanotubes and comparison with other dispersing Agents - D. Pramanik, Prabal K. Maiti ACS Appl. Mater. Interfaces, 9, 35287-35296 (2017)
  • Opening of large bandgap in metallic carbon nanotubes by mannose functionalized dendrimers: experiments and theory - K. S. Vasu, D. Pramanik, S. Kundu, Sridevi S., N. Jayaraman, M. Jain, Prabal K. Maiti, A. K. Sood J. Mater. Chem. C, 6, 6483-6488, (2018)
  • Kinetics of ligand–protein dissociation from all-atom simulations: are we there yet? - J.M.L. Ribeiro, S.T. Tsai, D. Pramanik, Y. Wang, P. Tiwary Biochemistry, 58 (3), 156-165 (2018)
  • Multi-dimensional spectral gap optimization of order parameters (SGOOP) through conditional probability factorization - Z. Smith, D. Pramanik, S.T. Tsai, P. Tiwary J. Chem. Phys., 149 (23), 234105 (2018)
  • Can one trust kinetic and thermodynamic observables from biased metadynamics simulations?: detailed quantitative benchmarks on millimolar drug fragment dissociation - D. Pramanik, Z. Smith, A. Kells, P. Tiwary J. Phys. Chem. B,123 (17), 3672-3678 (2019)
  • Metadynamics-based enhanced sampling protocol for virtual screening: case study for 3CLpro protein for SARS-CoV-2 – *S. Namsani , *D. Pramanik , Mohd A. Khan, S. Roy, J. K. Singh Journal of Biomolecular Structure and Dynamics, DOI:10.1080/07391102.2021.1892530 (2021) (*equal contribution)
  • Integrated docking and enhanced sampling based selection of repurposing drugs for SARS-CoV-2 by targeting host dependent factors – *A. Kumawat, *S. Namsani, *D. Pramanik, S. Roy, J. K. Singh Journal of Biomolecular Structure and Dynamics, (2021) (*equal contribution)
  • Phase behaviour of pure PSPC and PEGylated multi-component lipid and their interaction with Paclitaxel: An all-atom MD study - *Prantar Dutta , *D. Pramanik, Jayant K Singh Langmuir, 37, 10259-10271 (2021) (*equal contribution)
  • Dendrimer: A Novel Nanomaterials - D. Pramanik, S. Kanchi, G. Ayappa, P. K. Maiti In: Shankar S., Muller R., Dunning T., Chen G.H. (eds) Computational Materials, Chemistry, and Biochemistry: From Bold Initiatives to the Last Mile. Springer Series in Materials Science, vol 284. Springer, Cham. (2021)
  • Mechanistic insights of key host proteins and potential repurposed inhibitors regulating SARS-CoV-2 pathway - D. Pramanik, A Pawar, S Roy, J K Singh J Comput Chem, 43, 1237-1250 (2022)

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