Assistant Professor

Dr Seema Rani

Department of Chemistry

Interests

  1. Heterocyclic Chemistry
  2. Selective C–F Functionalization
  3. Total Synthesis of Natural Products

Education

2009

S.D. (P.G.) College, Panipat
BSc

2011

Kurukshetra University, Kurukshetra
MSc

2016

Indian Institute of Science Education and Research (IISER) Mohali, India
PhD

Experience

  • Sep 2022 - May 2023,Senior Scientific Manager (Team Leader) – Aragen Life Sciences Hyderabad, Telangana, India
  • Sep 2020 - Aug 2022, Senior Research Investigator S2 BBRC – Syngene International Limited
    Bengaluru, Karnataka, India
  • Aug 2017 - Aug 2020, Marie-Curie Post-Doc Fellow – Institute of Organic and Macromolecular
    Chemistry (IOMC) Friedrich Schiller University Jena, Germany
  • Dec 2016 - July 2017, Post-Doctoral Fellow – Schulich Faculty of Chemistry Technion, Israel

Research Interest

  • Development of new catalytic methods for the selective synthesis of heterocyclic compounds.
  • Selective C–F functionalization of trifluoromethylarenes
  • Total synthesis of bioactive natural products and bio-functional compounds for understanding of the biological phenomena’s.

Awards & Fellowships

  • 2021 – Bravo award – Bristol Myers Squibb (BMS) USA
  • 2020 – Marie Skłodowska-Curie Actions postdoctoral funding – European Union H2020
  • 2016 – Eli Lilly and Company Asia Outstanding Thesis Award – National Organic Symposium Trust (NOST) Council, India
  • 2015 – Senior Research Fellow (SRF) – Council of Scientific and Industrial Research (CSIR) India
  • 2011 – UGC-CSIR NET – Council of Scientific and Industrial Research (CSIR) India

Publications

  • Characterisation, (bio)synthesis and antimicrobial properties of drimenol-type sesquiterpenes of the fungal cultivar Termitomyces - N. B. Kreuzenbeck, S. Dhiman, D. Roman, J. Blume, I. Burkhardt, B. H. S. -Conlon, J. Fricke, H. Guo, H. Görls, M. Poulsen, J. S. Dickschat, T. Köllner, H. -D. Arndt and C. Beemelmanns - Communication Chemistry, 79, https://doi.org/10.1038/s42004-023-00871-z (2023)
  • Total synthesis of (‒)-thallusin and its dedicated analogues: Insight into the morphogenesis of Ulva - S. Dhiman, J. F. Ulrich, P. Wienecke, T. Wichard and H. - D. Arndt - Angewandte Chemie International Edition 61(39), e202206746 (2022)
  • Thallusin Quantification in Marine Bacteria and Algae Cultures - J. F. Ulrich, M. S Gräfe, S. Dhiman, P. Wienecke, H. -D. Arndt and T. Wichard - Marine Drugs 20(11), 690 (2022)
  • One-pot Relay Catalysis: Divergent Synthesis of furo[3,4-b]indoles and cyclopenta[b]indoles from3-(2-aminophenyl)-1,4-enynols - Manisha, S. Dhiman, J. Mathew and S. S. V. Ramasastry - Organic Biomolecular Chemistry 14, 5563-5568 (2016)
  • One-Pot Trimetallic Relay Catalysis: A Unified Approach for the Synthesis of β- Carbolines and Other [c]-Fused Pyridines - S. Dhiman, U. K. Mishra and S. S. V. Ramasastry - Angewandte Chemie International Edition 55(27), 7737-7741 (2016)
  • One-Pot Relay Gold(I) and Brønsted Acid Catalysis: Cyclopenta[b]annulations of Indoles Via Hydroamination/Nazarov-Type Cyclization Cascade of Enynols - S. Dhiman and S. S. V. Ramasastry – Organic Letter 17, 5116-5119 (2015)
  • Synthesis of Polysubstituted Cyclopenta[b]indoles via Relay Gold(I)/Brønsted Acid Catalysis - S. Dhiman and S. S. V. Ramasastry – Chemical Communication 51, 557-560 (2015)
  • Synthesis of 1, 2, 3-Trisubstituted Cyclopentannulated Benzothiophenes through an Acid-Mediated, Solvent-Free, One-Pot Domino Process - B. Satpathi, S. Dhiman and S. S. V. Ramasastry - European Journal of Organic Chemistry 2022-2026 (2014)
  • Di-and Triheteroarylalkanes via Self-Condensation and Intramolecular Friedel-Crafts Type Reaction of Heteroaryl alcohols - S. Dhiman and S. S. V. Ramasastry - Organic & Biomolecular Chemistry 11, 8030–8035 (2013)
  • Acid Catalyzed Ring Transformation of Benzofurans to Tri-and Tetrasubstituted Furans - S. Dhiman and S. S. V. Ramasastry - Journal of Organic Chemistry 78, 10472-10436 (2013)
  • Taming Furfuryl Cations for the Synthesis of Privileged Structures and Novel Scaffolds - S. Dhiman and S. S. V. Ramasastry - Organic & Biomolecular Chemistry 11, 4299-4303 (2013)
  • Taming Furfuryl Cations for the Synthesis of Privileged Structures and Novel Scaffolds - S. Dhiman and S. S. V. Ramasastry - Organic & Biomolecular Chemistry 11, 4299-4303 (2013)

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