Indian Institute of Science Education and Research, Pune India PhD
2018-2021-Postdoctoral researcher-The Ohio State University, Columbus, USA.
2017-2018-Postdoctoral Researcher-Emory University, Atlanta, USA.
2016-2017-Postdoctoral Researcher-The University of Utah, Salt Lake City, USA.
Design and construction of RNA nanoparticles for targeted delivery of combination therapeutics to cancer and other diseases.
Use of extracellular vehicles (EVs) as a biocompatible drug delivery vehicle for cancer and other diseases
Engineering EVs as a targeted delivery vehicle by decorating EVs' surface with cell-specific targeting ligands
Development of diagnostic tools for various diseases using RNA nanotechnology
Awards & Fellowships
2010-CSIR-Juniro Research Fellowship-IISER, Pune
2012– CSIR-senior Research Fellowship– IISER, Pune
2021-Ramanjuan Fellowship-SRM University
Fluorous Peptide Nucleic acids: PNA analogues with Fluorine in Backbone (γ-CF2-apg-PNA) Enhance Cellular uptake. S. Ellipilli and K. N. Ganesh. Journal of organic chemistry, 80, 9185-9191 (2015)
Perfluoroalkylchain conjugation as a New Tactic for Enhancing Cell Penetration of Peptide Nucleic Acids (PNA) via reducing the Nanoparticle size. S. Ellipilli, Murthy, R. K. N Ganesh. Chem. Comm., 52, 521-524 (2016)
Fluorinated Peptide Nucleic Acids with Fluoroacetyl Side Chain Bearing 5-(F/CF3)-Uracil: Synthesis and Cell Uptake Studies. S. Ellipilli, and K. N. Ganesh. Journal of organic chemistry, 81, 6364-6373 (2016).
Synthesis of Comb-shaped Branched DNA Using a Non-nucleosidic Branching Phosphoramidite. S. Ellipilli, J.D Phillips, and J. M. Heemstra. Organic & biomolecular chemistry, 16, 4659-4664 (2018)
Fluorogenic Photoaffinity Labeling of Proteins in Living Cells. T. M. Ayele, S. D. Knutson, S. Ellipilli, H. Hwang, and J. M. Heemstra, Bioconjugate Chemistry, 30, 1309-1313 (2019).
Multivalent Rubber-like RNA Nanoparticles for Targeted Co-delivery of Paclitaxel and MiRNA to Silence the Drug Efflux Transporter and Liver Cancer Drug Resistance. H. Wang, S. Ellipilli, W. Lee, X. Li, M. Vieweger, Y. Ho, P. Guo. Journal of Controlled Release, 330, 173-184 (2021). (Co-first author).
Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric materials in Nanotechnology and Nanomedicine----Specific Cancer Targeting with Undetectable Toxicity. D. Binzel, X. Li, N. Burns, E. Khan, W. Lee, L. Chen, S. Ellipilli, W. Miles, Y. Ho, P. Guo. Chemical review, 121, 7398-7467 (2021)