CSIR-Central Salt and Marine Chemicals Research Institute-Bhavnagar Ph.D.
Bhavnagar University M.Sc.
Bhavnagar University B.Sc.
2016-2018 – JSPS Postdoctoral Research Fellow – Tokyo Institute of Technology-Japan
Our main research focus is to produce renewable energy from microalgae. We are optimizing culture conditions to improve the growth and accumulation of TAGs/starch content in microalgae. We are also applying various chemical modulators to mitigate stress and improve the growth of microalgae. We are trying to develop integrated microalgal biorefinery to produce high-value compounds like phycobiliproteins, carotenoids along with biofuel and biofertilizers from microalgae. Apart from this, we are also interested to understand algal-bacterial interaction, particularly isolate and characterize the microalgae associated bacteria and finding their role in growth enhancement and inhibition in microalgae.
In a parallel, we are interested to understand the molecular mechanism behind the accumulation of carbon reserved molecules like TAGs/starch in microalgae. To understand this, we are utilizing model microalgae Cyanidioschyzon merolae and Chlamydomonas reinhardtii. Particularly we are interested to understand how checkpoint kinase target of rapamycin (TOR) is involved in growth as well as accumulation of TAGs/starch in microalgae. We are utilizing various biochemical and molecular genetic tools to understand TOR signaling in microalgae.
Awards & Fellowships
2016 – JSPS Post-Doctoral Research Fellowship – Japanese Society for Promotion of Science-Japan
2018-EMBO Travel Grant
2017-Outstanding contribution in reviewing-Bioresourec Technology-Elsevier
2015-Visiting Fellowship-University of Campinas (UNICAMP)- Sao Paulo-Brazil
2012- Senior Research Fellowship- Council of Scientific and Industrial Research (CSIR-SRF)-India
Japanese Society of Plant Physiologist
List of Publications
Target of rapamycin (TOR) signaling modulates starch accumulation via glycogenin phosphorylation status in the unicellular red alga Cyanidioschyzon merolae. Pancha I, Shima H, Higashitani N, Igarashi K, Higashitani A, Tanaka K, Imamura S. The Plant Journal 97(2019):485-499. IF-5.726.
Overexpression of a glycogenin, CmGLG2, enhances floridean starch accumulation in the red alga Cyanidioschyzon merolae. Pancha I, Tanaka K, Imamura S. Plant Signaling and Behavior 14(2019):1596718-1596724. IF-1.644.
Accelerated triacylglycerol production without growth inhibition by overexpression of a glycerol-3-phosphate acyltransferase in the unicellular red alga Cyanidioschyzon merolae. Fukuda S, Hirasawa E, Takemura T, Takahashi S, Chokshi K, Pancha I, Tanaka K, Imamura S. Scientific Reports 8(2018):12410-12421. IF-4.011.
The checkpoint kinase TOR (target of rapamycin) regulates expression of a nuclear-encoded chloroplast RelA-SpoT homolog (RSH) and modulates chloroplast ribosomal RNA synthesis in a unicellular red alga. Imamura S, Nomura Y, Takemura T, Pancha I, Taki K, Toguchi K, Tozawa Y, Tanaka K. The Plant Journal 94 (2018): 327-339. IF-5.726.
Nitrogen starvation-induced cellular crosstalk of ROS-scavenging antioxidants and phytohormone enhanced the biofuel potential of green microalga Acutodesmus dimorphus. Chokshi K, Pancha I, Ghosh A, Mishra S. Biotechnology for Biofuels 10 (2017): 60-72. IF-5.452.
Salinity induced oxidative stress alters the physiological responses and improves the biofuel potential of green microalgae Acutodesmus dimorphus. Chokshi K, Pancha I, Ghosh A, Mishra S. Bioresource Technology244 (2017):1376-1383, IF-6.669.
Comparative evaluation of chemical and enzymatic saccharification of mixotrophically grown de-oiled microalgal biomass for reducing sugar production. Pancha I, Chokshi K, Maurya R, Bhattacharya S, Bachani P, Mishra S. Bioresource Technology 204 (2016): 9-16. IF-6.669.
Microalgal biomass generation by phycoremediation of dairy industry wastewater: An integrated approach towards sustainable biofuel production. Chokshi K, Pancha I, Ghosh A, Mishra S. Bioresource Technology221 (2016): 455-460. IF-6.669.
Growth medium standardization and thermotolerance study of the freshwater microalga Acutodesmus dimorphus—a potential strain for biofuel production. Chokshi K, Pancha I, Maurya R, Paliwal C, Ghosh T, Ghosh A, Mishra S. Journal of Applied Phycology 28 (2016): 2687-2696. IF-2.635.
Cyanobacterial Pigments as Natural Anti-Hyperglycemic Agents: An In vitro Study. Ghosh T, Bhayani K, Paliwal C, Maurya R, Chokshi K, Pancha I, Mishra S. Frontiers in Marine Science 3 (2016): 146-155. IF-3.086.
Applications of de-oiled microalgal biomass towards development of sustainable biorefinery. Maurya R, Paliwal C, Ghosh T, Pancha I, Chokshi K, Mitra M, Ghosh A, Mishra S. Bioresource Technology 214 (2016): 787-796. IF-6.669.
Hydrolysate of lipid extracted microalgal biomass residue: An algal growth promoter and enhancer. Maurya R, Paliwal C, Chokshi K, Pancha I, Ghosh T, Satpati GG, Pal R, Ghosh A, Mishra S. Bioresource Technology 207 (2016): 197-204. IF-6.669.
Microalgal carotenoids: Potential nutraceutical compounds with chemotaxonomic importance. Paliwal C, Ghosh T, George B, Pancha I, Maurya R, Chokshi K, Ghosh A, Mishra S. Algal Research 15 (2016): 24-31. IF- 3.723.
Solar driven mass cultivation and the extraction of lipids from Chlorella variabilis: A case study. Bhattacharya S, Maurya R, Mishra SK, Ghosh T, Patidar SK, Paliwal C, Chokshi K, Pancha I, Maiti S, Mishra S. Algal Research 14 (2016): 137-142. IF-3.723.
Lipid extracted microalgal biomass residue as a fertilizer substitute for Zea mays Maurya R, Chokshi K, Ghosh T, Trivedi K, Pancha I, Kubavat D, Mishra S, Ghosh A. Frontiers in Plant Science 6 (2015): 1266-1275. IF-4.106.
Green synthesis, characterization and antioxidant potential of silver nanoparticles biosynthesized from de-oiled biomass of thermotolerant oleaginous microalgae Acutodesmus dimorphus. Chokshi K, Pancha I, Ghosh T, Paliwal C, Maurya R, Ghosh A, Mishra S. RSC Advances 6 (2016): 72269-72274. IF-3.049.
Bicarbonate supplementation enhanced biofuel production potential as well as nutritional stress mitigation in the microalgae Scenedesmus CCNM 1077. Pancha I, Chokshi K, Ghosh T, Paliwal C, Maurya R, Mishra S. Bioresource Technology 193 (2015): 315-323. IF-6.669.
Salinity induced oxidative stress enhanced biofuel production potential of microalgae Scenedesmus CCNM 1077. Pancha I, Chokshi K, Maurya R, Trivedi K, Patidar SK, Ghosh A, Mishra S. Bioresource Technology 189 (2015): 341-348. IF-6.669.
Enhanced biofuel production potential with nutritional stress amelioration through optimization of carbon source and light intensity in Scenedesmus CCNM 1077. Pancha I, Chokshi K, Mishra S. Bioresource Technology 179 (2015): 565-572. IF-6.669.
Selective carotenoid accumulation by varying nutrient media and salinity in Synechocystis CCNM 2501. Paliwal C, Pancha I, Ghosh T, Maurya R, Chokshi K, Bharadwaj SV, Ram S, Mishra S. Bioresource Technology 197 (2015): 363-368. IF-6.669.
Polyhydroxyalkanoate from marine Bacillus megaterium using CSMCRI's Dry Sea Mix as a novel growth medium. Dhangdhariya JH, Dubey S, Trivedi HB, Pancha I, Bhatt JK, Dave BP, Mishra S. International Journal of Biological Macromolecules 76 (2015): 254-261. IF-4.784.
Biofuel potential of the newly isolated microalgae Acutodesmus dimorphus under temperature induced oxidative stress conditions. Chokshi K, Pancha I, Trivedi K, George B, Maurya R, Ghosh A, Mishra S. Bioresource Technology 180 (2015): 162-171. IF-6.669.
Nitrogen stress triggered biochemical and morphological changes in the microalgae Scenedesmus CCNM 1077. Pancha I, Chokshi K, George B, Ghosh T, Paliwal C, Maurya R, Mishra S. Bioresource Technology 156 (2014): 146-154. IF-6.669.
Effects of different media composition, light intensity and photoperiod on morphology and physiology of freshwater microalgae Ankistrodesmus falcatus–A potential strain for bio-fuel production. George B, Pancha I, Desai C, Chokshi K, Paliwal C, Ghosh T, Mishra S. Bioresource Technology 171 (2014): 367-374. IF-6.669.
Biosorption of methylene blue by de-oiled algal biomass: equilibrium, kinetics and artificial neural network modelling. Maurya R, Ghosh T, Paliwal C, Shrivastav A, Chokshi K, Pancha I, Ghosh A, Mishra S. PloS One 9 (2014): e109545-e109557. IF-2.776.
Structural and functional stability of cellulase in aqueous-biamphiphilic ionic liquid surfactant solution. Bharmoria P, Mehta MJ, Pancha I, Kumar A. The Journal of Physical Chemistry B 118 (2014): 9890-9899. IF-2.923.
Fatty acids as biomarkers of microalgae. Sahu A, Pancha I, Jain D, Paliwal C, Ghosh T, Patidar S, Bhattacharya S, Mishra S. Phytochemistry 89 (2013): 53-58. IF-2.905.
Purification and characterization of haloalkaline thermoactive, solvent stable and SDS-induced protease from Bacillus: A potential additive for laundry detergents. Jain D, Pancha I, Mishra SK, Shrivastav A, Mishra S. Bioresource Technology 115 (2012): 228-236. IF-6.669.
Biodegradability studies of polyhydroxyalkanoate (PHA) film produced by a marine bacteria using Jatropha biodiesel byproduct as a substrate. Shrivastav A, Mishra SK, Pancha I, Jain D, Bhattacharya S, Patel S, Mishra S. World Journal of Microbiology and Biotechnology 27 (2011): 1531-1541. IF-2.652.
Isolation of promising bacterial strains from soil and marine environment for polyhydroxyalkanoates (PHAs) production utilizing Jatropha biodiesel byproduct. Shrivastav A, Mishra SK, Shethia B, Pancha I, Jain D, Mishra S. International Journal of Biological Macromolecules 47 (2010): 283-287. IF-4.784.
Effect of preservatives for food grade C-Phycoerythrin, isolated from marine cyanobacteria Pseudanabaena Mishra SK, Shrivastav A, Pancha I, Jain D, Mishra S. International Journal of Biological Macromolecules 47 (2010): 597-602.IF-4.784.
A thermoactive α-amylase from a Bacillus isolated from CSMCRI salt farm. Pancha I, Jain D, Shrivastav A, Mishra SK, Shethia B, Mishra S, Mohandas VP, Jha B. International Journal of Biological Macromolecules 47 (2010): 288-291. IF- 4.784.
Industrial Wastewater-Based Microalgal Biorefinery: A Dual Strategy to Remediate Waste and Produce Microalgal Bioproducts. Pancha I, Chokshi K, Mishra S. Application of Microalgae in Wastewater Treatment 2019 (pp. 173-193). Springer, Cham.
Oxidative Stress-Induced Bioprospecting of Microalgae. Chokshi K, Pancha I, Ghosh A, Mishra S. Systems Biology of Marine Ecosystems 2017 (pp. 251-276). Springer, Cham.
A process for the preparation of natural salt formulations for seawater substitution, mineral fortification S. Patent No. US9259663B2.
Integrated process for the production of oil bearing Chlorella variabilis for lipid extraction utilizing by-products of Jatropha methyl ester (JME) production. S. Patent No. US8741628B2.
Target of rapamycin (TOR) plays a critical role in carbon allocation in the unicellular red alga Cyanidioschyzon merolae” presented in EMBO workshop on target of rapamycin (TOR) signaling in photosynthetic eukaryotes from 14th to 19th May 2018 at Bischoffsheim, France.
Target of rapamycin (TOR) is a major signalling pathway that regulate starch accumulation in the unicellular red alga Cyanidioschyzon merolae” presented in 59th Annual meeting of the Japanese Society of Plant Physiologist from 27th to 30th March 2018 at Hokkaido university, Sapporo, Japan.
A thermoactive α-amylase from a Bacillus isolated from CSMCRI salt farm” Presented in Gujarat Science Congress, Gujarat University, Ahmadabad, 2010.